Research Associate

Job Opening for Research Associate

 

Applied Genetic Technologies Corporation, AGTC, is a privately-held clinical stage biotechnology company developing novel systems to deliver human therapeutics. Founded in Gainesville, FL, the company has successfully
entered clinical testing for their 2 lead programs and has received over $43
million in private equity funding, the most recent round of $11.8M from
blue-chip investors InterWest, Intersouth and MedImmune Ventures.

 Qualifications:

• BS or Masters Degree in Biological science, or related discipline,

• Minimum of 2 years experience.

Experience:

• Extensive hands-on expertise is required in the following: ELISA assay development, standard molecular biology techniques (western blot, immunoblots, silver stains, southern, etc), molecular cloning,

PCR, and mammalian cell culture.

• Basic knowledge of techniques in protein and/or virus purification, including FPLC is highly desirable.

 

Essential Duties and Responsibilities:

AGTC is looking for an experienced Research Associate to join its team and continue development of these novel treatments. While day to day activities will vary to fit the needs of the Company’s fast-paced projects,
typical responsibilities will include the following.

• Develop and qualify new assay methods, in particular enzyme-linked immunosorbent assays (ELISA) and a wide range of molecular assays.

• Complete testing of samples from preclinical and clinical studies to determine status of these studies and determine next steps.

• Conduct chromatography purification of recombinant adeno-associated virus (rAAV) and assist with further development of scalable and robust processes.

• Assist in the full characterization of recombinant herpes simplex virus (rHSV) for production of therapeutic rAAV as required for
regulatory compliance.

• Independently plan experiments and maintain relevant laboratory supplies and equipment as needed.

Language Skills:

• Required to communicate clearly in English—both written and oral.

Mission:

• The Research Associate is responsible for implementing a scientific plan, and working independently in the lab with minimal
supervision

Reporting Relationship:

The Research Associate will report directly to the Director, Preclinical Research & Development, and/or the Director, Process Development.

AGTC offers competitive salaries based on experience, with a full range of company paid benefits. In addition, AGTC will provide $4,000 toward the qualified candidate’s relocation expenses. EOE. AGTC maintains a drug free workplace.

 

Please send CV or resume to: Teresa Heal, Applied Genetic Technologies Corporation, 11801 Research Drive, STE D, Alachua, FL32615, theal@agtc.com

 

More about AGTC:

The Company demonstrated initial clinical proof of concept when its lead indication, for treatment of Alpha-1 Antitrypsin Deficiency (Alpha 1 an inherited form of emphysema), completed enrollment with
a positive safety profile and evidence of sustained protein expression. The
Phase II trial began in 2010 and is designed as a dose escalation trial to
obtain sustained and efficacious levels of protein expression. AGTC’s
ophthalmology focus began in 2004 with an agreement to develop therapies for
Wet Age-Related Macular Degeneration with Genzyme; a Phase I trial is currently
underway. AGTC’s independent ocular program for the treatment of Leber’s
Congenital Amaurosis (LCA) recently demonstrated safety and clinical proof of
concept with sustained expression of RPE65 in the clinic and a Phase II trial
began in 2009. AGTC augmented their ophthalmology portfolio by initiating
preclinical testing of treatments for two genetic forms of retinal
degeneration. The Company has a strong intellectual property position; its patents
protect not only the therapeutic delivery system, but also specific product
compositions, genes, delivery methods and proprietary, commercial-scale
production methods. AGTC’s mission is to combine this portfolio with unmatched
scientific and clinical expertise to create and bring new healthcare products
to the ophthalmology market.